CD Guadalajara vs FC Barcelona prediction 2025 pits a third-tier underdog against the reigning Copa del Rey champions in a David-versus-Goliath clash. Guadalajara’s spirited cup run faces a formidable test from Barcelona’s relentless attack, fresh off a five-match winning streak. This round of 32 encounter promises high stakes at a compact venue.
The match kicks off at 20:00 GMT+0 on Tuesday at Estadio Pedro Escartín in Guadalajara, a historic ground with an 8,000 capacity amplifying home passion. No referee is confirmed, though Copa del Rey fixtures typically see 4.5 cards per game. As part of the single-elimination round of 32, the winner advances to the last 16 in January 2026.
Betting Tips and Match Insights
CD Guadalajara vs FC Barcelona match prediction hinges on Barcelona’s attacking depth clashing with Guadalajara’s home resilience in the Copa del Rey. Recent form favors the Catalans, who average 3.0 goals in their last five, while Guadalajara’s defensive setup concedes sparingly at home. No head-to-head history exists, making current trends critical. Guadalajara’s scoring consistency meets Barcelona’s defensive leaks away. CD Guadalajara vs FC Barcelona prediction today points to a high-scoring Barcelona win.
CD Guadalajara Results
CD Guadalajara battles in Primera RFEF Group 1, relying on home grit to fuel their cup dreams against elite opposition. Their recent cup wins show fight. League struggles persist.
| Date | Competition | Matchup | Result | Guadalajara |
| 13/12/2025 | Primera RFEF | Real Madrid B vs Guadalajara | 3-1 | L |
| 07/12/2025 | Primera RFEF | Guadalajara vs Osasuna B | 1-0 | W |
| 02/12/2025 | Copa del Rey | Guadalajara vs Ceuta | 1-0 | W |
| 29/11/2025 | Primera RFEF | Pontevedra vs Guadalajara | 1-1 | D |
| 22/11/2025 | Primera RFEF | Guadalajara vs Athletic Bilbao B | 2-3 | L |
Guadalajara won two, drew one, and lost two in five, scoring six goals while conceding seven. Home victories showcased defensive resolve. Away losses exposed vulnerabilities. The cup win over Ceuta boosted morale. Form suggests competitiveness but limited firepower.
FC Barcelona Results
FC Barcelona dominates LaLiga with an unmatched attack, scoring freely while managing defensive inconsistencies on the road. Their cup pedigree looms large. Momentum builds.
| Date | Competition | Matchup | Result | Barcelona |
| 13/12/2025 | LaLiga | Barcelona vs Osasuna | 2-0 | W |
| 09/12/2025 | Champions League | Barcelona vs Eintracht Frankfurt | 2-1 | W |
| 06/12/2025 | LaLiga | Real Betis vs Barcelona | 3-5 | W |
| 02/12/2025 | LaLiga | Barcelona vs Atlético Madrid | 3-1 | W |
| 29/11/2025 | LaLiga | Barcelona vs Alavés | 3-1 | W |
Barcelona won all five, scoring 15 goals and conceding six. Home wins were clinical. Away games saw defensive lapses. Attack remains league-best at 2.9 goals per game. Form signals cup dominance.
Head-to-Head Between CD Guadalajara and FC Barcelona
No prior encounters exist between CD Guadalajara and FC Barcelona, typical for a third-tier side facing a LaLiga giant in early cup rounds. This lack of history shifts focus to form. Current trends guide predictions.
With no H2H data, Barcelona’s superior quality and scoring rate (3.0 goals per game) contrast Guadalajara’s 1.2 home average. Cup dynamics favor the favorites. Upset potential remains slim.
Predicted Lineups for CD Guadalajara vs FC Barcelona
Copa del Rey round of 32 ties often see LaLiga giants rotate heavily against lower-division opponents, giving minutes to backups and youth while resting stars for league duties. CD Guadalajara, with no reported injuries, fields their strongest side for this historic home game, while Barcelona manages absences like Gavi, Olmo, Araújo, and Szczęsny, likely starting a mixed XI heavy on regulars like Yamal and Raphinha.
CD Guadalajara Predicted Starting XI
Herráiz (GK), Stevens (DF), Serrano (DF), Richi (DF), Sergi (DF), Gallardo (MF), Nané (MF), Darío (AM), Cheki (AM), Olmo (AM), Cruz (FW).
FC Barcelona Predicted Starting XI
J. García (GK), Koundé (DF), Cubarsí (DF), Martín (DF), Baldé (DF), E. García (MF), Pedri (MF), Yamal (AM), Raphinha (AM), Rashford (AM), Torres (FW).
Key Factors to Watch
The round of 32 clash sees Guadalajara’s home defiance tested by Barcelona’s attacking juggernaut in a compact stadium. Injuries limit Barcelona’s depth. Motivation drives both sides.
- Guadalajara report no injuries, full squad available;
- Barcelona without Szczesny, Araújo, Gavi, Olmo;
- Guadalajara scored in eight of nine home games;
- Barcelona concede in 80% of away matches;
- No managerial changes or scandals reported;
- Guadalajara’s two-match home win streak;
- Barcelona’s five-match winning run across competitions;
- Estadio Escartín’s 8,000 fans boost home morale.
Free Tips on CD Guadalajara vs FC Barcelona
Barcelona’s flawless five-match winning streak, netting 15 goals while conceding just six, towers over Guadalajara’s mixed bag of two wins and two losses in five, with a modest six goals scored. The absence of head-to-head history shifts emphasis to current scoring rates, where Barcelona average 3.0 goals per game and Guadalajara 1.2 at home. These five sharp, data-backed tips exploit form disparities, player threats, and cup patterns for the Estadio Pedro Escartín showdown.
- Barcelona -2.5 handicap at around 1.90, they’ve covered in four of five wins this season against lower-tier opposition in cup/league;
- Over 3.5 goals at evens, Barcelona hit overs in their last four outings averaging 4.2 total while Guadalajara conceded three in recent home defeats;
- Raphinha anytime scorer at 1.80, he’s scored or assisted in eight of ten starts facing third-tier defenses;
- Barcelona over 8.5 corners near 2.00, they average 9.2 won away and Guadalajara concede 7.4 in high-possession mismatches;
- Barcelona clean sheet no at 2.50, Guadalajara scored in eight of nine home games and Barcelona conceded in 80% of road trips.
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CD Guadalajara vs FC Barcelona Match Prediction 2025
CD Guadalajara vs FC Barcelona odds heavily favor the visitors at 1.20, reflecting Barcelona’s 15 goals in five games against Guadalajara’s relegation-zone struggles in Primera RFEF. Barcelona’s attack, led by Yamal and Raphinha, should overwhelm Guadalajara’s defense, which conceded three to Real Madrid B. Despite Guadalajara’s home scoring (1.2 goals average), Barcelona’s 1.9 xG away and no clean sheets in ten road games suggest a 3-1 win. Guadalajara’s cup spirit may yield a goal, but Barcelona’s depth seals progression.
Our Prediction: CD Guadalajara 1-3 FC Barcelona
| Prediction Type | Prediction | Odds |
| Match Result | FC Barcelona Win | 1.1 |
| Both Teams to Score | Yes | 2.18 |
| Total Goals | Over 2.5 | 1.3 |
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